D-Mannose is a carbohydrate supplied as a pure powder.
In biopharma cell culture, D-Mannose can be used as an alternative to D-Glucose. With a slower uptake by cells, it helps to limit the formation of toxic by-products such as lactate.
As a building block for protein glycosylation, it helps to optimize the quality of therapeutic proteins by modulating their glycosylation profile - which is particularly relevant in the development and production of biosimilars.
Typical Applications
- Flexible production of biopharmaceuticals
Benefits at a glance
- Balanced energy supply
- Tailored glycosylation profile