cQrex® KC (N,N'-di-L-Lysyl-L-cystine dihydrochloride hydrate) is a chemically defined and non-animal-derived peptide designed to overcome the reactivity and solubility challenges associated with L-cysteine and its oxidized form L-cystine in cell culture media.
Thanks to its high solubility, cQrex® KC enables the formulation of concentrated basal, feed and perfusion media at neutral pH, therefore intensifying and simplifying the bioprocess.
By increasing the cell viability and cell-specific productivity, cQrex® KC also contributes to higher antibody titers and increased overall productivity of biological drugs.
In a fed-batch process, using cQrex® KC in combination with cQrex® GY supports the conversion from a dual-feed to a single-feed system.
Typical Applications
- Efficient production of biopharmaceuticals
Benefits at a glance
- Formulation of concentrated media
- Improved cell proliferation and viability
- Higher antibody titer and increased productivity
- Conversion to a single-feed system with reduced process complexity