Endexo® additives are low molecular weight oligomers used for modifying the surface properties of medical devices to improve performance and biocompatibility. The additives are added at low concentrations to a base polymer during standard manufacturing processes of device components.
Typical Applications
- Cardiovascular catheters and devices
- Neurological catheters and shunts
- Urological devices and stents
- Drainage catheters and devices
- Extracorporeal therapy components
- Blood circuits and filtration
Benefits at a glance
Endexo® additive technology is designed to improve the safety and biocompatibility of medical devices. By significantly reducing biological adhesion and biofilm formation, Endexo® additives offer a superior alternative to traditional medical device coatings.
- Compatible with a range of polymers and manufacturing processes: Passive surface modification that integrates seamlessly into existing manufacturing processes, with simplicity and minimal costs.
- Reduced thrombosis: Endexo® technology significantly reduces thrombus formation on blood-contacting devices by passively preventing blood component adhesion and activation.
- Reduced encrustation: Endexo® technology minimizes bacterial adhesion and encrustation on urological devices—without the use of antibiotics or active antimicrobials. By preventing colonization of encrustation-mediating bacteria like P. mirabilis, Endexo® helps reduce mineral buildup and prolong device functionality.
- Reduced bacteria adhesion: Endexo® technology passively resists bacterial adhesion and biofilm formation — without the use of antibiotics or active antimicrobials. Its unique surface chemistry has shown up to ~5 log (>99.9%) reductions in bacterial attachment across diverse conditions.
- Reduced friction properties: Endexo® technology reduces surface friction across along device surfaces, allowing easier movement at interfaces and improving blood flow and minimizing complications. Endexo® delivers up to 90% reduction in friction, leading to improved functionality.
- Durable and efficacious: Proven clinical safety and efficacy across numerous catheter and drainage devices.
