Accelerate skin recovery and strengthen its structure - where regenerative aesthetics meets longevity science
Vecollage® Fortify GP is a preservative-free skin-identical collagen polypeptide (sh-Polypeptide-69) designed to support skin regeneration, barrier resilience, and structural integrity - particularly in stressed, sensitive, or post-procedure skin.
Positioned at the intersection of regenerative aesthetics and longevity skincare, it helps translate biological regeneration into visible, lasting improvements in skin quality.
What it enables
- Supports faster skin recovery following aesthetic procedures
- Improves skin resilience and structural integrity over time
- Supports skin tone balance after treatments
Typical Applications
Benefits at a glance
- Barrier recovery & regeneration: Accelerates skin barrier recovery following minimally invasive and invasive procedures
- Structural resilience & dermal remodeling: Supports extracellular matrix renewal and increases dermal density
- Skin tone enhancement: Supports recovery-driven skin tone balance in stressed skin
- Preservative-free system: Self-preserved format without listed preservatives
- Low dose efficiency: Clinically effective at minimal use level (0.3%)
- Dermocosmetic compatibility: Ideal for post-procedure and high-tolerance formulations
- Clinically Validated: Proven efficacy across multiple aesthetic procedure types
- Differentiation Power: Positions products within regeneration and longevity-driven skincare
Find out more on https://intobeauty.evonik.com/product_area/?id=602
Product Details & Documents
Product Information
Markets & Applications
From anti-aging to skin longevity - where regenerative aesthetics and skincare converge
A fundamental shift in beauty
The beauty industry is moving from: Correcting visible signs of aging to preserving and extending skin function over time
This reflects a broader paradigm shift:
- Longevity science → extends biological function
- Regenerative aesthetics → restores biological function in skin
Aesthetic regeneration = the visible expression of longevity
Modern aesthetic treatments:
- Stimulate fibroblasts
- Rebuild collagen and the extracellular matrix (ECM)
- Trigger regeneration through controlled biological activation (activate healing cascades)
They represent the most tangible and visible application of longevity science
But regeneration does not stop in the clinic
Longevity cannot be achieved by a single treatment.
It requires continuous biological support:
- Before procedures → to optimize response
- After procedures → to accelerate recovery
- Long-term → to maintain skin structure and function
Supporting recovery-driven remodeling and structural resilience
Vecollage® Fortify supports key biological processes underlying skin aging and regeneration - through collagen balance and ECM integrity.
Vecollage® Fortify GP works through a dual mechanism:
1. Regeneration support
- Stimulates collagen I & III
- Supports ECM reorganization during recovery
2. Protection & stabilization
- Reduces collagen degradation (MMP regulation)
- Supports barrier repair and recovery processes
Aligned with biological responses to skin stress
Following aesthetic procedures or skin stress, biological processes include:
- Inflammatory signaling and altered cell communication
- Temporary disruption of barrier function
- Accelerated ECM remodeling and repair
By supporting collagen balance, barrier recovery, and ECM integrity, Vecollage® Fortify GP helps optimize regenerative efficiency and recovery outcomes, contributing to:
- Faster barrier recovery
- Improved structural regeneration
- More even skin tone (reduced visible post-inflammatory pigmentation)
Flexible Use Across Dermocosmetic Applications
Vecollage® Fortify GP is suitable for a wide range of dermocosmetic formats, particularly those aligned with sensitive or post‑procedure skin conditions.
Typical application areas include:
- Face and neck care
- Eye care formulations
- Dermocosmetic treatments
- Pre‑ and post‑procedure skincare
Proven compatibility with multiple formulation concepts supports its integration into diverse product formats, from toners to serums and hybrid cosmetic formats.
Clean, Preservative-Free and Responsibly Produced
Vecollage® Fortify GP is self-preserved without listed preservatives, supporting formulations tailored to sensitive or compromised skin.
It is produced via fermentation using renewable feedstock, reflecting modern expectations for ethical and sustainable ingredient sourcing.
Additional suitability signals include:
- Vegan composition
- Alignment with clean beauty positioning
- Compatibility with global dermocosmetic trends
Concept Inspiration
Formulation concepts demonstrate how the ingredient can be applied across modern formats:
- A dewy hydration serum stick combining collagen polypeptide and multiple hyaluronic acids for hydration-focused applications
- A lightweight fluid foundation delivering coverage alongside collagen support
- A low-viscosity toner designed for soothing and active delivery to sensitive skin
These concepts illustrate the ingredient’s versatility in both treatment and hybrid cosmetic formats.
Strengthen Skin Performance Around Aesthetic Procedures
Vecollage® Fortify GP supports skin recovery, reinforces dermal structure, and aligns with evolving consumer expectations for procedure‑inspired skincare.
FAQ
It is a biomimetic collagen polypeptide active (sh‑Polypeptide‑69) designed for dermocosmetic use. The ingredient supports skin before and after aesthetic procedures by combining collagen protection and stimulation with advanced cellular signaling mechanisms to reinforce dermal structure and function.
The ingredient combines two complementary actions: reducing degradation of existing collagen within the extracellular matrix while supporting new collagen synthesis. This dual approach helps maintain dermal integrity and supports visible improvements in skin structure and resilience.
The active uses exosome-mediated microRNA signaling to enhance communication between keratinocytes and fibroblasts. This interaction regulates gene expression linked to extracellular matrix preservation and strengthens the dermal‑epidermal junction, supporting overall skin architecture.
Yes, the ingredient is designed for use in pre‑ and post‑procedure skincare. It supports recovery of the skin barrier, dermal remodeling, and overall skin quality following minimally invasive and invasive aesthetic treatments.
It is suitable for face, neck, and eye care, as well as dermocosmetic and procedure-focused formulations. Its compatibility with multiple formats enables use in serums, toners, creams, and hybrid cosmetic products.
The ingredient is preservative-free and self-preserved, making it well-suited for formulations targeting sensitive or compromised skin. Its production via fermentation and vegan profile also align with clean beauty positioning.