Accelerate skin recovery and strengthen its structure - where regenerative aesthetics meets longevity science
Vecollage® Fortify GP is a preservative-free skin-identical collagen polypeptide (sh-Polypeptide-69) designed to support skin regeneration, barrier resilience, and structural integrity - particularly in stressed, sensitive, or post-procedure skin.
Positioned at the intersection of regenerative aesthetics and longevity skincare, it helps translate biological regeneration into visible, lasting improvements in skin quality.
What it enables
- Supports faster skin recovery following aesthetic procedures
- Improves skin resilience and structural integrity over time
- Supports skin tone balance after treatments
Typical Applications
Benefits at a glance
- Barrier recovery & regeneration: Accelerates skin barrier recovery following minimally invasive and invasive procedures
- Structural resilience & dermal remodeling: Supports extracellular matrix renewal and increases dermal density
- Skin tone enhancement: Supports recovery-driven skin tone balance in stressed skin
- Preservative-free system: Self-preserved format without listed preservatives
- Low dose efficiency: Clinically effective at minimal use level (0.3%)
- Dermocosmetic compatibility: Ideal for post-procedure and high-tolerance formulations
- Clinically Validated: Proven efficacy across multiple aesthetic procedure types
- Differentiation Power: Positions products within regeneration and longevity-driven skincare
Find out more on https://intobeauty.evonik.com/product_area/?id=602
Product Details & Documents
Product Information
Markets & Applications
From anti-aging to skin longevity - where regenerative aesthetics and skincare converge
A fundamental shift in beauty
The beauty industry is moving from: Correcting visible signs of aging to preserving and extending skin function over time
This reflects a broader paradigm shift:
- Longevity science → extends biological function
- Regenerative aesthetics → restores biological function in skin
Aesthetic regeneration = the visible expression of longevity
Modern aesthetic treatments:
- Stimulate fibroblasts
- Rebuild collagen and the extracellular matrix (ECM)
- Trigger regeneration through controlled biological activation (activate healing cascades)
They represent the most tangible and visible application of longevity science
But regeneration does not stop in the clinic
Longevity cannot be achieved by a single treatment.
It requires continuous biological support:
- Before procedures → to optimize response
- After procedures → to accelerate recovery
- Long-term → to maintain skin structure and function
Supporting recovery-driven remodeling and structural resilience
Vecollage® Fortify supports key biological processes underlying skin aging and regeneration - through collagen balance and ECM integrity.
Vecollage® Fortify GP works through a dual mechanism:
1. Regeneration support
- Stimulates collagen I & III
- Supports ECM reorganization during recovery
2. Protection & stabilization
- Reduces collagen degradation (MMP regulation)
- Supports barrier repair and recovery processes
Aligned with biological responses to skin stress
Following aesthetic procedures or skin stress, biological processes include:
- Inflammatory signaling and altered cell communication
- Temporary disruption of barrier function
- Accelerated ECM remodeling and repair
By supporting collagen balance, barrier recovery, and ECM integrity, Vecollage® Fortify GP helps optimize regenerative efficiency and recovery outcomes, contributing to:
- Faster barrier recovery
- Improved structural regeneration
- More even skin tone (reduced visible post-inflammatory pigmentation)
Flexible Use Across Dermocosmetic Applications
Vecollage® Fortify GP is suitable for a wide range of dermocosmetic formats, particularly those aligned with sensitive or post‑procedure skin conditions.
Typical application areas include:
- Face and neck care
- Eye care formulations
- Dermocosmetic treatments
- Pre‑ and post‑procedure skincare
Proven compatibility with multiple formulation concepts supports its integration into diverse product formats, from toners to serums and hybrid cosmetic formats.
Clean, Preservative-Free and Responsibly Produced
Vecollage® Fortify GP is self-preserved without listed preservatives, supporting formulations tailored to sensitive or compromised skin.
It is produced via fermentation using renewable feedstock, reflecting modern expectations for ethical and sustainable ingredient sourcing.
Additional suitability signals include:
- Vegan composition
- Alignment with clean beauty positioning
- Compatibility with global dermocosmetic trends
Concept Inspiration
Formulation concepts demonstrate how the ingredient can be applied across modern formats:
- A dewy hydration serum stick combining collagen polypeptide and multiple hyaluronic acids for hydration-focused applications
- A lightweight fluid foundation delivering coverage alongside collagen support
- A low-viscosity toner designed for soothing and active delivery to sensitive skin
These concepts illustrate the ingredient’s versatility in both treatment and hybrid cosmetic formats.
Strengthen Skin Performance Around Aesthetic Procedures
Vecollage® Fortify GP supports skin recovery, reinforces dermal structure, and aligns with evolving consumer expectations for procedure‑inspired skincare.
FAQ
Vecollage® Fortify GP is a preservative-free biomimetic collagen polypeptide (sh-Polypeptide-69) designed to support skin recovery, barrier resilience, and dermal remodeling. It helps accelerate recovery following skin stress or aesthetic procedures while improving visible skin quality over time.
Many post-procedure ingredients focus primarily on soothing, hydration, or barrier protection, such as panthenol, allantoin, hyaluronic acid, ceramides, or Centella asiatica extracts.
While these ingredients play an important role in supporting skin comfort and barrier function, Vecollage® Fortify GP goes a step further by supporting both recovery processes and structural skin remodeling. Through its skin-identical collagen technology, it helps improve recovery efficiency, dermal structure, and visible skin quality.
Vecollage® Fortify GP supports skin recovery and regeneration through a dual mechanism:
Regeneration support
- Supports collagen synthesis and extracellular matrix (ECM) remodeling during recovery
- Promotes the biological processes involved in tissue repair
Protection & stabilization
- Helps maintain collagen integrity through MMP regulation
- Supports barrier restoration and recovery processes
Following skin stress or aesthetic procedures, the skin undergoes a natural repair process involving barrier recovery, collagen remodeling, and tissue restructuring. By supporting these recovery-driven processes, Vecollage® Fortify GP helps improve regeneration efficiency, contributing to faster barrier recovery, increased dermal density, and improved skin quality over time.
In a placebo-controlled clinical study, Vecollage® Fortify GP demonstrated:
- 18% reduction in TEWL after 3 days
- 8% increase in dermal density after 56 days
- 42% reduction in visible hyperpigmentation after 28 days
These results demonstrate measurable improvements in barrier recovery, skin structure, and skin tone.
Aesthetic treatments activate the skin's natural regenerative processes, but visible outcomes depend on how effectively the skin recovers. Faster recovery helps restore barrier function, supports healthy tissue remodeling, and contributes to better overall skin quality following treatment.
Following aesthetic procedures or skin stress, inflammation can contribute to visible uneven pigmentation and skin tone irregularities.
By supporting recovery processes and helping the skin return more efficiently to a healthy state, Vecollage® Fortify GP helps reduce visible post-inflammatory pigmentation and promotes a more even-looking complexion.
Recovery is not only about restoring the skin barrier, it also involves rebuilding skin structure.
Dermal density is a measurable indicator of structural skin quality. The observed increase in dermal density demonstrates that Vecollage® Fortify GP supports recovery beyond the surface level, contributing to stronger, more resilient skin over time.
Yes. While Vecollage® Fortify GP was specifically developed and clinically evaluated for recovery-focused applications, it contains the same skin-identical collagen polypeptide technology that supports collagen balance, dermal remodeling, and skin quality.
As a result, Fortify GP can also be incorporated into daily skincare formulations targeting skin resilience, visible skin quality, and healthy skin aging. Its preservative-free format may be particularly attractive for sensitive skin, minimalist formulations, and products requiring a high level of formulation tolerance.
The key distinction between the two formats lies in their clinical substantiation and positioning:
Vecollage® Fortify L has been optimized for daily structural skin maintenance and clinically evaluated for visible anti-aging outcomes such as dermal density, firmness, elasticity, and wrinkle reduction.
Vecollage® Fortify GP is optimized for recovery-driven skin regeneration and has been clinically evaluated for recovery-related outcomes after aesthetic treatments (microneedling, laser resurfacing, chemical peeling) such as barrier repair, dermal density, and reduction of visible post-inflammatory pigmentation.
Depending on the desired positioning and formulation strategy, both formats can contribute to long-term skin quality and resilience.
Yes. Vecollage® Fortify GP is supplied in a preservative-free format and is particularly suitable for formulations targeting sensitive, stressed, or post-procedure skin.
Its combination of recovery support, barrier-focused performance, and formulation simplicity makes it well suited for high-tolerance skincare concepts.
Vecollage® Fortify GP is ideal for:
- Post-procedure skincare
- Revovery and regeneration serums
- Barrier-repair formulations
- Sensitive skin products
- Dermocosmetic skincare
- Skin resilience and longevity-focused concepts
- Minimalist or preservative-free formulations
Its versatility enables brands to create products that support both immediate recovery needs and long-term skin quality goals.