Alternative image

RESOMER® bioresorbable polymers for medical devices

RESOMER® biodegradable polymers for medical devices such as orthopedics, spine, dental, cardiovascular and wound healing applications

RESOMER® is the world’s leading portfolio of many standard, custom and specialized biodegradable polymers. The breadth and versatility of our portfolio enables us to match the properties and characteristics of our biodegradable polymers to address specific medical device application requirements. The RESOMER® portfolio has strong record for safety, biocompatibility, supply security and quality across more than 30 years of commercial use. Our reputation as industry innovators continues with the recent launch of different biodegradable polymers used for medical textile applications, PLA-PEGs that combine strength with rapid degradation and osteoconductive composites for bone fixation devices. We are also the world’s first supplier with a full portfolio of medical grade powder, granule and filament-based biodegradable polymers for 3D printing medical applications.

RESOMER® is the world’s leading brand for standard and custom biodegradable polymers used with implantable medical device applications

The RESOMER® portfolio of standard and custom biodegradable polymers includes a large, versatile selection of polymer families and compositions. Our polymers are based on

  • Lactide
  • Lactide-PEG
  • Caprolactone
  • Dioxanone
  • Glycolide
  • Composite

and can cover a wide range of medical device applications. Each of these RESOMER® products feature precise strength, elasticity and other mechanical and chemical properties, with degradation ranges ranging from just a month to more than four years.

The RESOMER® portfolio of bioresorbable polymers has earned a strong track record for efficacy, biocompatibility, safety and supply security over more than 30 years of commercial use. This portfolio of semi-crystalline and amorphous polymers are available in a range of standard and customizable forms to provide maximum versatility in the development of innovative bioresorbable devices.

In addition to the development and supply of biomaterials for orthopedic devices such as interference screws, suture anchors and fracture plates, Evonik also offers specific materials for cardiovascular devices such as vascular closures and vascular stents; for wound healing applications such as sutures and ligating clips; and other applications including dental membranes and tissue engineering scaffolds.

Some of the many advantages of RESOMER® include:
  • robust quality and safety data
  • wide range of degradation profiles
  • tailorable mechanical properties
  • easy processing
  • stable after sterilization

Explore our portfolio of standard and custom polymers

A strong portfolio of standard polymers for high performance bioresorbable implant devices

Polymer nameInherent viscosity (dl/g)CompositionDegradation
timeframe*
End group
RESOMER®
C 202
0.20 - 0.26Poly(caprolactone)not measuredEster
RESOMER®
C 203
0.35 - 0.43Poly(caprolactone)not measuredEster
RESOMER®
C 209
0.8 - 1.0Poly(caprolactone)> 2 yearsEster
RESOMER®
C 212
1.13 - 1.38Poly(caprolactone)> 2 yearsEster
RESOMER®
C 217
1.53 - 1.87Poly(caprolactone)> 2 yearsEster
RESOMER®
G 205 S 
1.05 - 1.25Poly(glycolide)< 5 weeksEster
RESOMER®
GC 753 S
1.15 – 1.55Poly(glycolide-co-ε-caprolactone)< 4 weeksEster
RESOMER®
GL 903 S
1.05 - 1.25Poly(glycolide-co-L-lactide) < 5 weeks Ester
RESOMER®
GT 643 S
1.0 – 1.4Poly(glycolide-co-trimethylene carbonate)< 8 weeks  Ester
RESOMER®
L 206 S
0.8 - 1.2Poly(L-lactide)> 3 yearsEster
RESOMER®
L 207 S
1.5 - 2.0Poly(L-lactide)> 3 yearsEster
RESOMER®
L 209 S
2.6 - 3.2Poly(L-lactide)> 3 yearsEster
RESOMER®
L 210 S
3.3 - 4.3Poly(L-lactide)> 3 yearsEster
RESOMER® Composite
L 210 S HA
3.0 - 4.0Poly(L-lactide) with 25 % Hydroxylapatite< 3 yearsEster
RESOMER®
LC 703 S
1.3 - 1.8Poly(L-lactide-co-ε-caprolactone) 70:30not measuredEster
RESOMER®
LT 706 S
1.2 - 1.6Poly(L-lactide-co-trimethylene carbonate) 70:30not measuredEster
RESOMER®
LG 824 S
1.7 - 2.6Poly(L-lactide-co-glycolide) 82:181 - 2 yearsEster
RESOMER®
LG 855 S
2.5 - 3.5Poly(L-lactide-co-glycolide) 85:151 - 2 yearsEster
RESOMER® Composite
LG 855 S β-TCP
2.0 – 3.5Poly(L-lactide-co-glycolide)
with 30% β-tricalcium phosphate
< 1.5 yearsEster
RESOMER®
LG 857 S
5.0 - 7.0Poly(L-lactide-co-glycolide) 85:151 - 2 yearsEster
RESOMER®
LP t 16
3.8 - 4.8Poly(L-lactide-co-PEG) triblock< 12 monthsAcid
RESOMER®
LP t 46
1.8 - 2.6Poly(L-lactide-co-PEG) triblock< 7 monthsAcid
RESOMER®
LR 704 S
2.0 - 2.8Poly(L-lactide-co-D,L-lactide) 70:302 - 3 yearsEster
RESOMER®
LR 706 S
3.3 - 4.2Poly(L-lactide-co-D,L-lactide) 70:302 - 3 yearsEster
RESOMER® Composite
LR 706 S β-TCP
2.8 - 4.2Poly(L-lactide-co-D,L-lactide)
with 30% β-tricalcium phosphate
< 2 yearsEster
RESOMER®
LR 708
5.7 - 6.5Poly(L-lactide-co-D,L-lactide) 70:302 - 3 yearsAcid
RESOMER®
LRP t 7016
3.3 - 4.2Poly(L-lactide-co-D,L-lactide-co-PEG) triblock< 9 monthsAcid
RESOMER®
LRP t 7046
1.5 - 2.3Poly(L-lactide-co-D,L-lactide-co-PEG) triblock< 6 monthsAcid
RESOMER®
R 207 S
1.3 - 1.7Poly(D,L-lactide)1 - 2 yearsEster
RESOMER®
X 206 S
1.5 - 2.2*Polydioxanone< 6 monthsEster

*Approximate degradation times are intended to guide polymer selection. Actual resorption times are dependent upon the process and application and must be empirically determined.

 

RESOMER® Select: Custom biodegradable polymers for medical devices

If adjustable customization is required for a target medical device application, our best-in-class RESOMER® Select portfolio of biodegradable polymers can be easily tailored at full potential to address your specific needs. All RESOMER® Select products can be made to order via tunable characteristics including

  • Monomers
  • Monomer ratios
  • Polymer architecture
  • End groups
  • Inherent viscosity

Additional customizations can also be made to provide our biodegradable polymers in forms such as filaments, powders, tubes or granules.

cute little girl putting a cross over impossible on blackboard

Whitepaper: Next-Generation Solutions for Bone Reconstruction: The Role of Evonik’s RESOMER® in BellaSeno’s 3D-Printed Scaffold Technology

Alternative image


ANY QUESTIONS LEFT? JUST CONTACT US.

"Our global team of experts is ready to support you with all questions around our RESOMER® polymers and their wide range of applications. Contact us to profit from more than 30 years of application know-how in the field of medical devices and find your individual solution!"

 

Mandy Roovers-Wiermans
Business Development Manager Medical Device Solutions

Alternative image