Evonik is a leader in the large-scale manufacturing of highly potent active pharmaceutical ingredients (HPAPIs). These complex APIs are increasingly crucial in the pharmaceutical pipeline, particularly for cancer therapies. The synthesis of many HPAPIs involves complex processes that utilize technologies such as peptide coupling, continuous processing, and biocatalysis.
With extensive project experience and a robust audit track record, we can efficiently scale production from small lab quantities to commercial volumes exceeding 450 kg. You benefit from our diverse technology portfolio and exemplary safety protocols.
Our global presence ensures supply security. At our site in Tippecanoe, Lafayette, Indiana in the U.S. we can run six different HPAPIs simultaneously, with a total capacity of 170 m³ and batch sizes exceeding 400 kg. At our Hanau facility in Germany, we support the development of complex APIs requiring containment down to an occupational exposure limit (OEL) of 5 ng/m³, with both GMP and non-GMP custom manufacturing capabilities available.