The world’s only dual action coating enabling precise and fail-safe colonic delivery
Phloral® creates multiple opportunities to target small molecules, biologics and live biotherapeutic products to the distal regions of the gastrointestinal tract for enhanced localized or systemic therapy. The advanced technology utilizes independent yet complementary release mechanisms for site-specific release in the colon:
- EUDRAGIT® S 100, the pH triggered polymer, maintains the integrity of the coating upon arrival to the colon
- The polysaccharide is efficiently digested by trillions of bacteria present in the large intestine to guarantee release upon arrival.
What makes Phloral® unique?
Phloral® is a clinically validated technology demonstrating consistent release and improved results in patients with Inflammatory Bowel Disease and C. Difficile Infection, as well as in subjects without GIT diseases. The first Phloral® product has completed Phase 3 clinical studies with more than 800 patients.
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"Our global team of experts is ready to support you with all questions around our product and service portfolio for oral drug delivery. Contact us to profit from more than 70 years of application know-how!"
Felix Hofmann
Director Formulation & Application Services
