Boost cell culture performance with special carbohydrates
Evonik offers high-purity, plant-derived specialty carbohydrates designed to enhance the performance of cell culture media in biopharmaceutical production. They provide a balanced energy supply and serve as critical building blocks for protein glycosylation, helping you achieve superior product quality and process efficiency.
Functions and applications of specialty carbohydrates in cell culture
In traditional cell culture, D-Glucose is a key energy source. However, its rapid consumption often leads to excessive lactate formation, which can impair cell growth and productivity. Other monosaccharides such as D-Galactose and D-Mannose are often metabolized at a lower rate. They can be used to partially or fully replace glucose, offering a controlled energy release that supports cell culture performance.
Additionally, carbohydrates play a key role in modulating protein glycosylation, a crucial quality attribute for therapeutic proteins. This is particularly relevant in the case of biosimilars to ensure a higher degree of similarity to the originator drugs. For example, D-Galactose or N-Acetyl-D-Mannosamine can be supplemented to CHO cell cultures to tune the glycosylation profile of proteins.
Partner with Evonik
With decades-long expertise in cell culture ingredients, Evonik is a trusted partner to leading biopharma companies worldwide. Our robust supply chain, and deep technical know-how ensure consistent quality and performance across your cell culture platforms.
Also meet us these shows & events
ANY QUESTIONS? JUST CONTACT US.
"If you are looking for ways to more efficient bioprocessing and improved performance, our innovative cell culture solutions will be of great value to you. Contact us to find out how we can support and meet your needs."
Dr. Kristina Klinker
Business Development Manager
