VECOLLAN®: A breakthrough recombinant collagen platform for life science that is safe, sustainable, highly soluble and commercially scalable
Evonik has developed VECOLLAN®, an advanced recombinant collagen platform now available in a grade suitable for use in clinical trials. It is made via fermentation-based processes and devoid of animal- or human-derived materials. It will, for the first time, provide medical, pharmaceutical, cell culture and tissue engineering markets with a highly soluble and highly pure form of collagen that is safe, sustainable and commercially scalable. VECOLLAN® features a triple helix structure and other tunable properties that are designed to mimic many of the attributes of natural collagen so that it can reliably interact with cells and tissues and be readily absorbed or remodeled by the body. It is also designed for supply in a range of forms or shapes, and to be compatible with a range of processing and cross-linking technologies. Get in touch with us using the contact button on the side to learn more about the platform, or to request an R&D sample.
Evonik’s recombinant collagen platform is differentiated from other animal or biosynthetic sources
Animal-sourced collagen, currently the main source of collagen for use in life sciences applications, can be associated with batch-to-batch variability, potential transmission of diseases or pathogens, adverse immunogenic or allergic reactions, and non-sustainable sourcing methods. By comparison, our VECOLLAN® recombinant collagen can be produced under precisely controlled conditions via an established fermentation-based process. In addition to being sustainable and suitable for vegan use, this process delivers a high level of purity that is easily reproducible at any R&D, clinical or commercial scale. In addition to ensuring batch-to-batch reproducibility, the VECOLLAN® platform is designed to provide customers with a source of medical or pharmaceutical-grade biomaterial that is highly soluble at physiological pH and available to customers to support the development and scale-up of their life science applications.
VECOLLAN® has possibilities in many different application areas.
Our VECOLLAN® recombinant collagen platform at a glance
| Products | Class of material | Property | Processibiity | Application area |
|---|---|---|---|---|
| VECOLLAN® | Recombinant collagen-like peptide | Bioresorbable (Long-term implantable) |
|
Development, scale-up and manufacturing services for your product applications complementing recombinant collagen supply
Evonik is one of the world’s leading strategic partners and solution providers for implantable medical devices, drug delivery, cell culture and tissue engineering applications. Services we can offer include the synthesis, design and production of biomaterials according to ISO 13485 requirements. Processing support includes the rapid prototyping of samples with a range of 3D printing technologies, as well as the analysis of thermal, surface, mechanical and molecular properties, and studies to assess factors including biocompatibility, bioavailability and stability. We offer also the development and cGMP manufacturing of complex oral and parenteral drug products including those based upon microparticles, nanoparticles and drug-loaded implants.
Want to learn more about the VECOLLAN® recombinant collagen platform?
